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The Neural Correlates of Age-related Differences in Episodic Memory: A Perspective from fMRI

Michael D. Rugg, Ph.D.  Distinguished Chair in Behavioral and Brain Sciences, Co-director of the Center for Vital Longevity, University of Texas at Dallas

Presented: March 28, 2014

ABSTRACT: Episodic memory declines markedly with increasing age. I will describe a series of studies in which fMRI was employed to identify the neural correlates of episodic memory encoding and retrieval in differently aged individuals. Together, the findings demonstrate that age-related memory decline results from changes in efficacy of several mnemonically-relevant processes, including inter-regional interactions, but that it is not associated with major re-organization of the functional networks that support encoding or retrieval.

BIOGRAPHY: Distinguished Chair in Behavioral and Brain Sciences and director of the Center for Vital Longevity at the University of Texas at Dallas. He was formerly director of the Center for the Neurobiology of Learning and Memory at University of California, Irvine. His research focuses on the cognitive and neural bases of episodic memory, and how these vary across the lifespan and in neurological disease.

Information shared in this lecture was requested be held from public access. MRN employees can access the presentation here.

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