Principal Investigators //
- Corey Hill Allen, PhD >
- Nathaniel Anderson, PhD >
- Vince Calhoun, PhD >
- Felicha Candelaria-Cook, PhD >
- Arvind Caprihan, PhD >
- Vince Clark, PhD >
- Eric D. Claus, PhD >
- Aparna Gullapalli, PhD >
- Faith Hanlon, PhD >
- Carla Harenski, PhD >
- Jon Houck, Ph.D. >
- Kent Hutchison, PhD >
- Kent A. Kiehl, PhD >
- Dean O. Kuethe, PhD >
- Jeffrey D. Lewine, PhD >
- J. Michael Maurer, PhD >
- Andrew R. Mayer, PhD >
- John Phillips, MD >
- Sephira Ryman, PhD, MS
- Julia M. Stephen, PhD >
- David B. Stone, PhD >
- Andrei Vakhtin, Ph.D. >
- Claire E. Wilcox, MD >
Sephira Ryman, PhD, MS
Assistant Professor
Dr. Sephira Ryman is a clinical neuropsychologist who uses behavioral and multimodal neuroimaging techniques to understand the cognitive deficits in psychiatric and neurological conditions. Her research examines how modifiable mechanisms and neuropathological processes impact cognition and functional outcomes. She aims to characterize the nature of these processes as well as identify meaningful diagnostic and prognostic biomarkers. She is interested in translating the knowledge gained from these studies to develop neuromodulatory approaches to improve cognitive dysfunction.
For more information about specific studies, to volunteer for a study, or meet Dr. Ryman's research team, visit links on the left hand side of the page.
Selected Publications //
- MRI biomarkers of motor and non-motor symptoms in Parkinson’s disease >
- Impaired Midline Theta Power and Connectivity During Proactive Cognitive Control in Schizophrenia >
- Sexual risk-taking and subcortical brain volume in adolescence >
- Fronto-Parietal gray matter and white matter efficiency differentially predict intelligence in males and females >
- Proactive response inhibition abnormalities in the sensorimotor cortex of patients with schizophrenia >
- Developmental Cognitive Neuroscience of Adolescent Sexual Risk and Alcohol Use >
- Quantity yields quality when it comes to creativity: a brain and behavioral test of the equal-odds rule >
- Subcortical intelligence: Caudate volume predicts IQ in healthy adults >
- Functional Brain Networks Contributing to the Parieto-Frontal Integration Theory of >
- Sex differences in the relationship between white matter connectivity and creativity >
- Brain biochemistry and personality: a magnetic resonance spectroscopy study >
- Proactive and reactive cognitive control rely on flexible use of the ventrolateral prefrontal cortex >
- Neurosensory Deficits Vary as a Function of Point of Care in Pediatric Mild Traumatic Brain Injury >
- Look Hear! The Prefrontal Cortex is Stratified by Modality of Sensory Input During Multisensory Cognitive Control >
- Graph Metrics of Structural Brain Networks in Individuals with Schizophrenia and Healthy Controls: Group Differences, Relationships with Intelligence, and Genetics >
Cognitive and Psychiatric Functioning in Aging
MRI biomarkers have been studied in individual neurodegenerative diseases, but there have been minimal amounts of research examining how MRI biomarkers relate to cognitive and psychiatric dysfunction accross neurodegenerative conditions. This study will examine, longitudinally and observationally, individuals diagnosed with neurodegenerative conditions and how those measures relate to cognitive and psychiatric functioning and whether those measures can predict functional outcomes over time. This research ultimately aims to facilitate earlier detection and improve treatments for neurodegenerative conditions. A significant gain in understanding the utility of MRI biomarkers to identify the presence and progression in neuropathological processes across neurodegenerative conditions is expected over the course of this study.
