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Traumatic Brain Injury //

Reward-Guided Decision Making in Healthy Participants and Brain Injured Patients

The purpose of this project is to characterize the brain mechanisms underlying maladaptive reward processing in patients with mild traumatic brain injury (mTBI), with a focus on psychiatric symptoms in patients. Such a reward processing approach has seldom been adopted in the investigation of psychiatric symptoms in mTBI. The current protocol will involve extensive testing of cognitive and affective abilities in acute mTBI patients greater than 3 months post-injury – when psychiatric sequelae are particularly pronounced. An age- and education-matched sample of neurologically-healthy participants will also complete the study. The study will use a combination of questionnaires/ self-report assessment, behavioral assessments, and both structural (MPRAGE, DTI), and functional (resting-state fMRI, task fMRI) methodologies.

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