Principal Investigators //

Matthew Shane, PhD

Assistant Professor of Translational Neuroscience-Independent Consultant

Matthew Shane

Dr. Shane specializes in the study of neurocognitive and neuroaffective abnormalities in antisocial and substance abusing populations. Involved in the Mind Research Network mobile core program, Dr. Shane utilizes functional magnetic resonance imaging (fMRI) and electroencephalography (EEG) within correctional facilities to better elucidate and distinguish the neural correlates of criminal psychopathy and substance abuse disorders.  

Dr. Shane’s research is focused on the integrity of error monitoring, empathic processing and emotional control within these overlapping, but distinct disorders. ​

Email Dr. Shane

Selected Publications //

Addiction & Forensics Research

Substance use disorders have received increasing, well-deserved attention from both researchers and public policy makers due to the detrimental and costly impact drugs of abuse have on individuals and society. Substance dependence is often characterized by compulsive use of a substance that provides short-lived pleasure and relief of anxiety, despite being aware of the harmful effects of these substances and the negative impact that it has on one’s life.  Nearly 80% of incarcerated populations meet criteria for a drug and/or alcohol use disorder, and our established relationships with prisons across the country is a valuable resource for conducting research into the neural and psychological factors which promote substance abuse.  One promising avenue of this research examines functional brain activity during expectancy of reward and while monitoring conflicting influences over behavior in tasks which require specific responses.  Psychopathy is also strongly associated with substance abuse.  With access to genetic data, brain data, and long-range behavioral outcomes of those who struggle with substance abuse, we are developing more sophisticated models of the factors contributing to this problem, which may highlight the most promising strategies for prevention and treatment.