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Sarah W. Feldstein Ewing, PhD

Assistant Professor of Translational Neuroscience

Assistant Professor of Translational Neuroscience, The Mind Research Network

Adjunct Assistant Professor, Psychology Department, University of New Mexico

Adjunct Assistant professor, University Honors Program, University of New Mexico

Assistant Professor, Child & Adolescent Psychiatry, University of New Mexico

Licensed Clinical Psychologist, New Mexico

This e-mail address is being protected from spambots. You need JavaScript enabled to view it

 

Currently, substance use interventions are only modestly effective. The goal of our laboratory is to employ translational studies to (1) determine the driving factors underlying successful treatment outcomes, (2) develop more efficacious interventions, and (3) evaluate the efficacy of interventions. Ultimately, we aim to improve health outcomes and reduce current disparities for high-risk adolescents and adults of all backgrounds.

We are currently conducting three lines of research. The first line aims to investigate health disparities and differential treatment effects and treatment components among a culturally diverse sample of adolescents using motivational interviewing (1R01AA017878-01A2; PI: Feldstein Ewing).

The second line focuses on the use of translational approaches to evaluate developmental factors that may influence the efficacy of psychosocial interventions. We aim to determine whether specific neurocognitive factors (e.g., relational reasoning, reward sensitivity) as assessed in using fMRI paradigms, contribute to the effectiveness of interventions for adolescents at different periods of neurodevelopment.

Our third line is focused on evaluating a novel integration of a psychosocial intervention (MI) and an in-vivo neuroimaging paradigm to determine the active mechanisms of the intervention. We are currently conducting research investigating in-vivo neural activation in response to client speech to evaluate if differential activation occurs, and whether it relates to long-term substance use outcomes. Preliminary results from this study have been promising (1R03DA027892-01 and DE-FG02-08ER64581; PI: Feldstein Ewing).

 

Education

B.A., Psychology, Macalester College,  

M.S., Clinical Psychology, University of New Mexico

Ph.D., Clinical Psychology, University of New Mexico

Predoctoral Internship, Pediatric Psychology, Brown University Medical School

Postdoctoral Fellowship, Addiction Research, Mind Research Network

 

Awards and Honors
•    Research Society on Alcoholism/NIAAA Junior Investigator Award, 2009
•    NIAAA/Young Scientists Travel Award for the International Society of Psychiatric Genetics, Osaka Japan, 2008    
•    Garland Award for Excellence in Clinical and Research Work with Adolescents, University of New Mexico, 2005

Selected Publications

  1. Feldstein Ewing, S. W., Filbey, F. M., Hendershot, C., McEachern, A.D., & Hutchison, K. E. (in press). A proposed model of the neurobiologicalmechanisms underlying psychosocial alcohol interventions:  The example of motivational interviewing and functional magnetic resonance imaging. Journal of Studies on Alcohol and Drugs.
  2. Claus, E. D., Feldstein Ewing, S. W., Filbey, F. M., Sabbineni, A., & Hutchison, K.E. (in press). Identifying neurobiological phenotypes associated with alcohol use disorder severity. Neuropsychopharmacology.
  3. Hendershot, C. S., Bryan, A. D., Feldstein Ewing, S. W., Claus, E. D., & Hutchison, K. E. (in press). CHRM2, disinhibition and substance use: Evidence for mediated genetic effects in adolescence.  Journal of Abnormal Child Psychology.
  4. Schmiege, S., Feldstein Ewing, S. W., Hendershot, C., & Bryan, A. D. (in press). Positive outlook as a moderator of the effectiveness of an HIV/STI intervention with adolescents in detention. Health Education Research.
  5. Feldstein Ewing, S. W., Venner, K. L., Mead, H. K., & Bryan, A. D. (2011). Exploring racial/ethnic differences in substance use: A preliminary theory-based investigation with juvenile justice-involved youth. BMC Pediatrics, 11 (71).
  6. Feldstein Ewing, S. W., Filbey, F. M., Sabbineni, A., & Hutchison, K. E. (2011).  How psychosocial alcohol interventions work: A preliminary look at what fMRI can tell us.  Alcoholism: Clinical and Experimental Research, 35(4), 643-651.
  7. Tolou-Shams, M., Feldstein Ewing, S. W., Tarantino, N., & Brown, L. K. (2010). Crack and cocaine use among adolescents in psychiatric treatment: Associations with HIV risk.  Journal of Child and Adolescent Substance Abuse, 19(2), 122-134.
  8. Feldstein Ewing, S. W., Filbey, F. M., Chandler, L. D., & Hutchison, K. (2010).  Exploring the relationship between depressive and anxiety symptoms and neuronal response to alcohol cues.  Alcoholism: Clinical and Experimental Research, 34(3), 396-403.  PMID: 20028366 
  9. LaChance, H. A., Feldstein Ewing, S. W., Bryan, A., & Hutchison, K. (2009). What makes group MET work?  A randomized controlled trial of college student drinkers in mandated alcohol diversion.  Psychology of Addictive Behaviors, 23(4), 598-612. 
  10. Feldstein Ewing, S. W., LaChance, H. A., Bryan, A., & Hutchison, K. (2009). Do genetic and individual risk factors moderate the efficacy of motivational enhancement therapy?  Drinking outcomes with an emerging adult sample. Addiction Biology, 14(3), 356-365. 
  11. Feldstein, S. W. & Forcehimes, A. A. (2007).  Motivational interviewing with underage college drinkers:  A preliminary look at the role of empathy and alliance.  The American Journal of Drug and Alcohol Abuse, 33, 1-10.
  12. Feldstein, S. W. & Miller, W. R. (2007).  Does subtle screening work? A review of the Substance Abuse Subtle Screening Inventory (SASSI).  Addiction, 102(1), 41-50. 
  13. Feldstein, S. W. & Miller, W. R. (2006).  Substance abuse and risk-taking among adolescents.  Journal of Mental Health, 15(6), 1-11. 
  14. Feldstein, S. W., Venner, K. L., & May, P. A. (2006).  American Indian/Alaska Native alcohol-related incarceration and treatment.  American Indian and Alaska Native Mental Health Research:  The Journal of the National Center, 13(3), 1-22.
  15. Feldstein, S. W. & Ginsburg, J. I. D. (2006).  Motivational interviewing with dually diagnosed adolescents in juvenile justice settings:  A review.  Brief Treatment and Crisis Intervention, 6(3), 218-233.

 

Links

•    https://www.mrn.org/docs/RISK.mov

 

Professional Memberships

•    Association for Behavioral and Cognitive Therapies (ABCT)

•    Society for Research in Child Development (SRCD)

•    Research Society on Alcoholism (RSA)

•    Motivational Interviewing network of Trainers (MINT)

•    American Psychological Association – Divisions 50 (Addictions) and 54 (Pediatric Psychology).

 

Grant Review Committees

•    2005, Netherlands Maternal and Child Health Program

•    2009-present, NIH (NIAAA/NIDA) Challenge grant cycle

•    2009-present, NIH (NIAAA) ZAA1 DD (01) review group

Research Support (ongoing and completed)

 

•    1R01 AA017878-01A2                 (PI: Feldstein Ewing)                        8/25/2009-7/31/2014

AMICA: Assessing the Fit of Motivational Interviewing by Cultures with Adolescents

NIH/NIAAA

The objective of this application is to evaluate the efficacy of a brief individual intervention (MI) for problem drinking behaviors with a sample of justice-involved Hispanic and Caucasian adolescents to determine if this intervention is differentially effective between Hispanic and Caucasian adolescents.

Role: PI

 

•    1R03DA027892-01                                   (PI: Feldstein Ewing)                        4/1/2010-3/31/2011

Adolescent Response to Psychotherapy: The Role of Neuronal Networks

NIH/NIDA

This proof of concept proposal seeks to innovatively integrate biological and behavioral approaches using functional MRI (fMRI) to evaluate the neural and genetic underpinnings of the initiation and maintenance of behavior change (reduced cannabis use) during and following a widely disseminated psychosocial intervention for adolescents with cannabis use disorders.

Role: PI

 

•    DE-FG02-08ER64581                              (PI: Feldstein Ewing)                        2/1/2010-1/31/2011

Evaluating Motivational Interviewing with College Students through Genetic and Neuroimaging Approaches (GEMINI)

MRN/DOE

This proposal seeks to innovatively integrate biological and behavioral approaches using functional MRI (fMRI) to evaluate the neural and genetic underpinnings of the initiation and maintenance of behavior change (reductions in binge drinking) during and following a widely disseminated, and NIAAA-indicated, psychosocial intervention for heavy drinking young adults.

Role: PI

 

•    1R01 AA017390-01                                            (PI: Bryan)                    1/4/2009-1/3/2014

NIH/NIAAA/NIDA

Alcohol, Marijuana, and Risky Sex: Group Interventions with Detained Adolescents

This research is designed to implement and carefully evaluate new intervention technologies that have the goal of decreasing alcohol- and marijuana-related sexual risk behavior in highly vulnerable young people.

Role: Co-I

 

•    1R01 AA017390-01                                            (PI: Bryan)                                10/1/2007-9/30/2012

NIH/NIAAA

HIV prevention with adolescents: Neurocognitive deficits and treatment response

This research is designed to understand the genetic and neurocognitive predispositions that contribute to sexual risk behaviors that place justice-involved adolescents at high risk of unintended pregnancy and STDs including HIV/AIDS. The findings will help us to design better interventions to decrease alcohol-related sexual risk behavior in this population of highly vulnerable young people.

Role: Co-I

 

•    NIH Loan Repayment Program    (PI: Feldstein Ewing)                        7/1/2010-6/31/2012

NIH/NIAAA

Role: PI

 

•    NIH Loan Repayment Program    (PI: Feldstein Ewing)                        7/1/2008-6/31/2010

NIH/NIAAA

Role: PI

 

•    MRN Internal Award (like R21)               (PI: Feldstein Ewing)                        4/1/2008-9/1/2009

The Role of Neurocognition and Genetics in Adolescent Substance Abuse Behavior: A Pilot

MRN/DOE

This aims of this work were to better understand the neural mechanisms that underlie adolescent substance abuse, to determine the relationship between genetic and biological predispositions and adolescent substance abuse, and to determine adolescents’ comfort with a brief, empirically supported clinical intervention. This study set the groundwork for subsequent investigations of how genetic and biological predispositions influence adolescents’ response to clinical interventions, as well as how to tailor and devlop more effective adolescent substance abuse interventions.

Role: PI

 

Research Team

Postdoctoral Fellows:

•    Amber D. McEachern, PhD, Wichita State University

•    Hilary K. Mead, PhD, University of Washington

 

Graduate Assistants:

•    Mandy Owens

•    Alisha Wray, PhD 

Research Assistants:

•    Elisa DeVargas

•    Amanda Ortiz-Briggs

•    Dustin Truitt

 

Former Team Members and Current Successes:

•    Lindsay Chandler, Clinical Research Coordinator, University of Utah

•    Sam DeWitt, Graduate Student in Cognition and Neuroscience, University of Texas at Dallas

 

CONTACT INFORMATION:

Sarah W. Feldstein Ewing, PhD

Assistant Professor of Translational Neuroscience

The Mind Research Network

1101 Yale Boulevard
Albuquerque, NM 87131
Tel: (505) 277-4211, Fax: (505) 272-8002

This e-mail address is being protected from spambots. You need JavaScript enabled to view it

 

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