Principal Investigators //
- Vince Calhoun, PhD
- Arvind Caprihan, PhD >
- Zikuan Chen, PhD >
- Vince Clark, PhD >
- Eric D. Claus, PhD >
- Carla Harenski, PhD >
- Kent Hutchison, PhD >
- Kent A. Kiehl, PhD >
- Jeffrey D. Lewine, PhD >
- Jingyu Liu, PhD >
- Andrew R. Mayer, PhD >
- John Phillips, MD >
- Sergey Plis, PhD >
- Matthew Shane, PhD >
- Vaughn R. Steele, PhD >
- Julia M. Stephen, PhD >
- Jing Sui, PhD >
- Jessica Turner, PhD >
- Qingbao Yu, PhD >
Vince Calhoun, PhD
Executive Science Officer and Director, Image Analysis and MR Research
Professor of Translational Neuroscience
The Mind Research Network
Distinguished Professor, Departments of Electrical and Computer Engineering (primary),
Neurosciences, Computer Science, and Psychiatry
The University of New Mexico
Dr. Calhoun develops techniques for making sense of complex brain imaging data. Because each imaging modality has limitations, the integration of these data is needed to understand the healthy and especially the disordered human brain.
Dr. Calhoun has created algorithms that map dynamic networks of brain function, structure and genetics, and how these are affected while being stimulated by various tasks or in individuals with mental illness such as schizophrenia.
For more information on Dr. Calhoun, please refer to his Curriculum Vitae or visit the Medical Image Analysis Lab. His CV includes his academic career, as well as grant history, professional service, a partial list of publications and a full bibliography.
Dr. Calhoun recently received fellowship designations for both the American Association for the Advancement of Science (AAAS) and the Institute of Electrical and Electronics Engineers (IEEE).
The organizations recognize Dr. Calhoun for his contributions to human brain research. One of Calhoun’s most significant accomplishments is his development of advanced algorithms that identify how brain regions ‘talk’ to one another either during a specific task or when at rest.
He also recently earned the A. Earl Walker Neuroscience Research Award, which recognizes outstanding contributions to basic or clinical research in neuroscience by a member of the faculty in any UNM department.
Selected Publications //
- Nonlinear magnitude and linear phase behaviors of T2* imaging: theoretical approximation and Monte.. >
- Associations between DNA methylation and schizophrenia-related intermediate phenotypes - A gene….. >
- Intrinsic functional brain mapping in reconstructed 4D magnetic susceptibility (χ) data space >
- Mutually temporally independent connectivity patterns: A new framework to study resting state….. >
- Long-term effects of marijuana use on the brain, >
- Baseline effects of transcranial direct current stimulation on glutamatergic neurotransmission…... >
- Complexin2 modulates working memory-related neural activity in patients with schizophrenia. >
- Lateralization of resting state networks and relationship to age and gender >
- Sparse models for correlative and integrative analysis of imaging and genetic data >
- Harnessing modern web application technology to create intuitive and efficient data visualization… >
- The rich get richer: brain injury elicits hyperconnectivity in core subnetworks >
- Impact of autocorrelation on functional connectivity >
- Methylation Patterns in Whole Blood Correlate with Symptoms in Schizophrenia Patients >
- Abnormal brain structure in youth who commit homicide >
- A Review of Multivariate Analyses in Imaging Genetics >
Fusing multi-task and multi-modal brain imaging data and indentify the potential biological markers
Each brain imaging modality reports on a different aspect of the brain with different strengths and weaknesses and there are now literally thousands of putative imaging biomarkers. This project will develop multivariate methods which use higher order statistics to combine diverse information in a scalable manner, identify correspondence among data types and also provide a sophisticated data sharing and management system.
Exploring similarity and differences among schizophrenia and bipolar disorder by combining fMRI and
This project will develop an exploratory data fusion model which combines 2 multivariate methods and is able to identify correspondence among multiple data types. We aim to apply this model to schizophrenia and bipolar disorder via an fMRI-DTI fusion, which can identify both shared and disease-specific brain abnormalities from multiple perspectives (brain function and structure).
Brain Connectivity Changes in Individual Subjects with Neuropsychological Disease
Methods to provide better characterization of functional and structural brain network connectivity in patients with schizophrenia and addiction are being developed.(Calhoun et al., 2009; Greicius et al., 2007; Lynall et al., 2010; van den Heuvel et al., 2010) The goal is to provide accurate markers of disease progression in individual subjects with neuropsychological diseases associated with brain connectivity alterations.